Colposcopy in Istanbul: Examination and Cervical Biopsy

Quick answer: Colposcopy in Istanbul for abnormal Pap smear or HPV results. What happens during the examination, when biopsy may be needed, preparation, results and follow-up.

By Dr Alparslan Demir · Specialist in Obstetrics and Gynaecology · Updated 2 October 2026

Why might colposcopy be recommended?

Colposcopy is a magnified examination of the cervix, usually recommended after certain HPV or Pap smear results. It is not a cancer diagnosis and it is not an operation. Its purpose is to identify areas that may need closer assessment and, when appropriate, a small biopsy.

The reason for referral matters. HPV 16 or HPV 18, high-grade cytology such as HSIL or ASC-H, glandular abnormalities, persistent high-risk HPV, previous CIN treatment and the visibility of the transformation zone can lead to different clinical decisions.

What happens during the procedure?

The examination starts similarly to a routine gynaecological examination. A speculum is placed so the cervix can be seen. The colposcope remains outside the body. Dilute acetic acid and, in selected cases, iodine are used to make epithelial patterns easier to assess.

Colposcopy only

If no suspicious area requires tissue sampling, the appointment may end after visual assessment and documentation.

Colposcopy with biopsy

If an area needs histological assessment, one or more small targeted biopsies may be taken. The pathology result, not the visual impression alone, determines whether CIN is present.

Does colposcopy hurt?

Most patients describe the speculum examination as pressure or discomfort. A cervical biopsy may cause a brief cramp or pinching sensation. Pain experience varies, so tell the clinician if you are anxious, have had a difficult pelvic examination before, or have a condition that may affect comfort.

What should I bring?

  • Your complete HPV report, including genotype information if available.
  • Your Pap smear/cytology report, not only the summary line.
  • Previous colposcopy and biopsy reports.
  • Any record of LEEP, cone biopsy or treatment for CIN2/3.
  • Your pregnancy status and relevant medications.

When is endocervical sampling considered?

Assessment of the endocervical canal depends on the referral result, age, pregnancy status, whether the transformation zone can be fully visualised and the suspected type of abnormality. It is not performed automatically for every patient. In pregnancy, endocervical curettage is not performed.

After colposcopy or biopsy

After a biopsy, light spotting or dark discharge may occur. Follow the specific aftercare instructions you are given. Seek medical review for heavy bleeding, severe pain, fever or other symptoms that are not expected from a minor biopsy.

Related English guides

Arrange a colposcopy consultation in English

Dr. Alparslan Demir sees patients at his private practice in Şişli, Istanbul. You can discuss your HPV or Pap smear report, the reason for referral and the proposed next steps directly in English.

Fees, reports and travel plans

Before the procedure, confirm what the quoted fee covers and whether any biopsy or pathology charge is separate. Bring your complete reports and ask how and when results will be reviewed. If you are travelling, discuss your departure date and follow-up arrangements before booking your return journey; pathology results may require more time than the examination itself.

English consultation in Şişli, Istanbul

Dr Alparslan Demir · Specialist in Obstetrics and Gynaecology
Halaskargazi Cad. No: 226/1, Çiftkurt Apartment, Şişli / Istanbul

You may bring previous HPV, Pap smear, colposcopy, biopsy and pathology reports in English or Turkish.

International patients · Contact and directions · +90 212 284 07 08